The GSDMD antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to Gasdermin D, and GSDMD. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The GSDMD antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death